In vivo and in vitro immunomodulatory activities of Trichilia glabra aqueous leaf extracts |
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| Authors: | Benencia F Courrèges M C Coulombié F C |
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| Affiliation: | Dpto. Química Biológica, Facultad de Ciencias Exactas y Naturales, Pabellón II, Piso 4, Ciudad Universitaria, Buenos Aires, Argentina. fbenen@qb.fcen.uba.ar |
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| Abstract: | The effects of Trichilia glabra (Meliaceae) aqueous leaf extract on mouse lymphocytes were studied. The in vitro proliferation of T and B lymphocytes was completely impaired. Besides, the extract significantly diminished both antibody and delayed hypersensitivity responses in treated mice. These results suggest that the extract exerts a marked immunomodulatory effect on the murine immune system. |
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