| 多巴胺受体系统在诱发产生的大麻酚类戒断症状中不起主要作用(英文) |
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| 引用本文： | M Clara SANUDO-PENA,Michelle FORCE,TSOU Kang,Gabrielle McLEMORE,Langdon ROBERTS,J Michael WALKER. 多巴胺受体系统在诱发产生的大麻酚类戒断症状中不起主要作用(英文)[J]. Acta pharmacologica Sinica, 1999, 0(12) |
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| 作者姓名： | M Clara SANUDO-PENA Michelle FORCE TSOU Kang Gabrielle McLEMORE Langdon ROBERTS J Michael WALKER |
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| 作者单位： | Schrier Research Laboratory，Departments of Psychology and Neuroscience，BrownUniversity，Providence RI 02912，USA，Schrier Research Laboratory，Departments of Psychology and Neuroscience，BrownUniversity，Providence RI 02912，USA，Schrier Research Laboratory，Departments of Psychology and Neuroscience，BrownUniversity，Providence RI 02912，USA，Schrier Research Laboratory，Departments of Psychology and Neuroscience，BrownUniversity，Providence RI 02912，USA，Schrier Research Laboratory，Departments of Psychology and Neuroscience，BrownUniversity，Providence RI 02912，USA，Schrier Research Laboratory，Departments of Psychology and Neuroscience，BrownUniversity，Providence RI 02912，USA |
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| 摘 要： | AIM: To determine the dopaminergic systeminvolvement in precipitated cannabinoid withdrawalsyndrome. METHODS: The dopamine D_1 receptorantagonist SCH23390 or the dopamine D_2 receptorantagonost sulpiride was administered to rats chronicallytreated with either △~9-tetrahydrocannabinol (THC) orvehicle. Subjects were then injected with eitherSR141716A or vehicle and behavior was observed for1 h. RESULTS: Administration of the cannabinoidreceptor antagonist SR141716A to animals chronicallytreated with THC as described by Tsou et al (1995)
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| 关 键 词： | 大麻酚类 四氢大麻酚 SR141716A 物质禁断综合症 多巴胺D_1受体 多巴胺D_2受体 多巴胺拮抗剂 瘙痒症 疼痛 |
Dopaminergic system does not play a major role in the precipitated cannabinoid withdrawal syndrome |
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| M Clara SANUDO-PENA,Michelle FORCE,TSOU Kang,Gabrielle McLEMORE,Langdon ROBERTS,J Michael WALKER. Dopaminergic system does not play a major role in the precipitated cannabinoid withdrawal syndrome[J]. Acta pharmacologica Sinica, 1999, 0(12) |
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| Authors: | M Clara SANUDO-PENA Michelle FORCE TSOU Kang Gabrielle McLEMORE Langdon ROBERTS J Michael WALKER |
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| Abstract: | |
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| Keywords: | cannabinoids tetrahydrocannabinol SR141716A substance withdrawal syndrome dopamine D1 receptors dopamine D2 receptors dopamine antagonists pruritus pain |
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