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通心方对冠心病三支血管病变心室重构及心血管事件的影响
引用本文:邢健东,董耀荣,赵颖,程蓉歧,冯其茂,吴美平,王胜林,王俊龙,张蕾. 通心方对冠心病三支血管病变心室重构及心血管事件的影响[J]. 中国中医急症, 2010, 19(10)
作者姓名:邢健东  董耀荣  赵颖  程蓉歧  冯其茂  吴美平  王胜林  王俊龙  张蕾
作者单位:1. 上海市中医医院,上海,200071
2. 上海交通大学医学院附属新华医院,上海,200092
基金项目:上海市卫生局中医药科研基金项目 
摘    要:目的观察通心方对冠心病三支血管病变患者心室重构的临床疗效及对心血管事件的影响。方法入选患者随机分为两组,治疗组在基础治疗基础上给予通心方,对照组仅给予基础治疗,疗程6个月;分别于治疗前后观察左室舒张末期容积指数(LVEDVI)、左室收缩末期容积指数(LVESVI)、射血分数(EF)、E峰/A峰比值(E/A)、室壁厚度(WT)、左室重量指数(LVMI)和室壁运动指数(WMI)的变化,并随访1年内心血管事件发生情况。结果治疗组治疗后LVEDVI下降,LVMI下降,WMI下降;对照组治疗后E/A比值降低、LVMI升高,较治疗组变化明显;其治疗后WMI明显升高。两组随访1年,心血管事件发生率近似。结论通心方能改善冠心病三支病变患者的心室重构和心室的舒张功能,对1年内心血管事件无明显影响。

关 键 词:冠心病  三支病变  心室重构  心血管事件  中药通心方

Effect of Tongxin Decoction on Ventricular Remodeling and Cardiovascular Events in Patients with Triple-vessel Coronary Artery Disease
XING Jian-dong,DONG Yao-rong,ZHAO Ying,et alShanghai Traditional Chinaese Medicine Hospital. Effect of Tongxin Decoction on Ventricular Remodeling and Cardiovascular Events in Patients with Triple-vessel Coronary Artery Disease[J]. Journal of Emergency in Traditional Chinese Medicine, 2010, 19(10)
Authors:XING Jian-dong  DONG Yao-rong  ZHAO Ying  et alShanghai Traditional Chinaese Medicine Hospital
Affiliation:XING Jian-dong,DONG Yao-rong,ZHAO Ying,et alShanghai Traditional Chinaese Medicine Hospital(Shanghai 200071)
Abstract:Objective: To observe the effect of Tongxin Decoction on ventricular remodeling and cardiovascular events in patients with triple-vessel coronary artery disease.Methods: Patients with triple-vessel coronary artery disease were randomly divided into the treatment group and the control group.Besides the basic treatment in two groups,the Tongxin Decoction was used in the treatment group.These therapies were lasted for 6 months.Some indices being observed by the two-dimensional echocardiography were compared be...
Keywords:Coronary artery disease  Triple-vessel disease  Ventricular remodeling  Cardiovascular events  Tongxin Decoction  
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