| 阿司匹林肠溶片水性包衣技术的研究 |
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| 引用本文： | 王召,张钧寿.阿司匹林肠溶片水性包衣技术的研究[J].中国药科大学学报,1991,22(3):154-157. |
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| 作者姓名： | 王召 张钧寿 |
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| 作者单位： | 中国药科大学药剂学研究室，中国药科大学药剂学研究室，中国药科大学药剂学研究室 1988级研究生，1990届实习生 |
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| 摘 要： | 从崩解时限、泄漏率及药物稳定性等方面对阿司匹林的有机溶媒包衣和水性包衣进行了比较,实验表明,两种包衣系统均能产生良好的肠溶特性;扫描电镜结果显示,在水性胶乳系统的成膜过程中,单个聚合物粒子已完全融合成均匀、连续的膜,其外观的光滑程度超过了有机溶媒系统。
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| 关 键 词： | 肠溶丙烯酸聚合物 胶乳 水性包衣技术 阿司匹林 |
Studies on Aqueous Coating Technique for Acetylsalicylic Acid Enteric Tablets |
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| Wang Zhao,Zhang Junshou,Zhang Wei Division of Pharmaceutics.Studies on Aqueous Coating Technique for Acetylsalicylic Acid Enteric Tablets[J].Journal of China Pharmaceutical University,1991,22(3):154-157. |
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| Authors: | Wang Zhao Zhang Junshou Zhang Wei Division of Pharmaceutics |
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| Abstract: | A comparative evaluation was conducted between organic solvent coating and aqueous coating systems for acetylsalicylic acid tablets in disintegration time, diffusion of active material and drug stability. Result showed that both the systems could present satisfied enteric characters. Scanning electron micrographs revealed that in the course of film formation for aqueous latex system the individual polymer particles were completely coalesced into a homogeneous and continuous film whose surface was even smoother than that produced using an organic system. |
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| Keywords: | Enteric acrylic polymer Latex Aqueous coating technique Aspirin |
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