| 溃疡性结肠炎患者中血小板计数与一氧化氮的相关性及其临床意义 |
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| 引用本文： | 刘成义,杜美燕. 溃疡性结肠炎患者中血小板计数与一氧化氮的相关性及其临床意义[J]. 中国实用医药, 2010, 5(36): 55-57 |
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| 作者姓名： | 刘成义 杜美燕 |
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| 作者单位： | 1. 内蒙古消化研究所/包头医学院第二附属医院消化科,014030
2. 包头市扶贫医院妇产科 |
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| 摘 要： | 目的探讨活动性溃疡性结肠炎（UC）中血小板计数和一氧化氮（NO）的关系。方法选取溃疡性结肠炎病例173例,根据Truelove评分分为轻、中、重度,正常对照组40例,统计检测各组的血小板计数和一氧化氮水平。结果活动性UC患者血清一氧化氮水平及血小板计数明显增高,并与病情的轻重有关（P〈0.05）。血小板计数、一氧化氮分别与溃疡性结肠炎的严重程度分级有关,并且二者呈正相关。结论抑制NO在治疗活动性溃疡性结肠炎方面具有重要临床意义。
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| 关 键 词： | 溃疡性结肠炎 血小板计数 一氧化氮水平 |
Ivestigation of Serum NO Levels and Platelet Count in Patients With Ulcerative Colitis |
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| Abstract: | Objective To investigate the correlation between levels of serum nitric oxide and platelet count,immune dysfunction exists in patients with ulcerative colitis（UC）.Methods 173 patients with UC were divided into 3 group：mild group,moderate group and severe group.40 health volunteers as control group,analysis of variance（ANOVA）on statistics or detections platelet count and serum NO of 4 groups.Results Levels of serum NO in patients with ulcerative colitis were significantly high and related to severe degrees of the disease.Conclusion Inhibiting undue NO is importantly significant to treat dysfunctional UC. |
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| Keywords: | Ulcerative colitis Platelet count Nitric oxide |
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