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cIMPACT‐NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT‐Utrecht meeting on future CNS tumor classification and grading
Authors:David N Louis  Pieter Wesseling  Kenneth Aldape  Daniel J Brat  David Capper  Ian A Cree  Charles Eberhart  Dominique Figarella‐Branger  Maryam Fouladi  Gregory N Fuller  Caterina Giannini  Christine Haberler  Cynthia Hawkins  Takashi Komori  Johan M Kros  HK Ng  Brent A Orr  Sung‐Hye Park  Werner Paulus  Arie Perry  Torsten Pietsch  Guido Reifenberger  Marc Rosenblum  Brian Rous  Felix Sahm  Chitra Sarkar  David A Solomon  Uri Tabori  Martin J van den Bent  Andreas von Deimling  Michael Weller  Valerie A White  David W Ellison
Abstract:cIMPACT‐NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy) was established to evaluate and make practical recommendations on recent advances in the field of CNS tumor classification, particularly in light of the rapid progress in molecular insights into these neoplasms. For Round 2 of its deliberations, cIMPACT‐NOW Working Committee 3 was reconstituted and convened in Utrecht, The Netherlands, for a meeting designed to review putative new CNS tumor types in advance of any future World Health Organization meeting on CNS tumor classification. In preparatory activities for the meeting and at the actual meeting, a list of possible entities was assembled and each type and subtype debated. Working Committee 3 recommended that a substantial number of newly recognized types and subtypes should be considered for inclusion in future CNS tumor classifications. In addition, the group endorsed a number of principles—relating to classification categories, approaches to classification, nomenclature, and grading—that the group hopes will also inform the future classification of CNS neoplasms.
Keywords:brain tumors  central nervous system  classification  neoplasms
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