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Diagnosing peripheral neuropathy in South‐East Asia: A focus on diabetic neuropathy
Authors:Rayaz A Malik  Aimee Andag‐Silva  Charungthai Dejthevaporn  Manfaluthy Hakim  Jasmine S Koh  Rizaldy Pinzon  Norlela Sukor  Ka Sing Wong
Abstract:Burning and stabbing pain in the feet and lower limbs can have a significant impact on the activities of daily living, including walking, climbing stairs and sleeping. Peripheral neuropathy in particular is often misdiagnosed or underdiagnosed because of a lack of awareness amongst both patients and physicians. Furthermore, crude screening tools, such as the 10‐g monofilament, only detect advanced neuropathy and a normal test will lead to false reassurance of those with small fiber mediated painful neuropathy. The underestimation of peripheral neuropathy is highly prevalent in the South‐East Asia region due to a lack of consensus guidance on routine screening and diagnostic pathways. Although neuropathy as a result of diabetes is the most common cause in the region, other causes due to infections (human immunodeficiency virus, hepatitis B or C virus), chronic inflammatory demyelinating polyneuropathy, drug‐induced neuropathy (cancer chemotherapy, antiretrovirals and antituberculous drugs) and vitamin deficiencies (vitamin B1, B6, B12, D) should be actively excluded.
Keywords:Diagnosis  Peripheral neuropathy  South‐East Asia
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