| 参麦注射液对5/6肾切除大鼠肾脏的保护作用研究 |
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| 引用本文： | 文礼湘,陈北阳,屈波,何泽云. 参麦注射液对5/6肾切除大鼠肾脏的保护作用研究[J]. 湖南中医药大学学报, 2002, 22(2): 10-11,23 |
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| 作者姓名： | 文礼湘 陈北阳 屈波 何泽云 |
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| 作者单位： | 湖南中医学院基础课部,湖南,长沙,410007 |
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| 基金项目： | 国家自然科学基金项目(39900199) |
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| 摘 要： | 目的：探讨参麦注射液对5／6肾切除大鼠肾小球、肾小管的保护作用。方法：采用5／6肾切除造成大鼠肾功能衰竭模型，使用光学显微镜观测参麦注射液腹膜透析后肾小球、肾小管形态结构的变化。结果：参麦注射液具有促进受损的肾小球、肾小管修复作用，其作用与参麦注射液抗肾间质炎相关。结论：参麦注射液具有保护5／6肾切除大鼠肾脏的作用，这种保护作用与其抗肾间质炎功能相关。
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| 关 键 词： | 参麦注射液 肾功能衰竭 肾脏形态学 肾间质炎 |
| 文章编号： | 1000-5633(2002)02-0010-02 |
Protective Effect of Shenmai Injection on the Kidneys of Rats with 5/6 Nephrectomy |
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| Wen Lixiang,Chen Beiyang,Qu Bo,et al. Protective Effect of Shenmai Injection on the Kidneys of Rats with 5/6 Nephrectomy[J]. Journal of Traditional Chinese Medicine University of Hunan, 2002, 22(2): 10-11,23 |
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| Authors: | Wen Lixiang Chen Beiyang Qu Bo et al |
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| Abstract: | Objective To study the protective effect of Shenmai injection (SMI) on renal glomerulus and tubule in rats with 5/6 nephrectomy. Methods By means of light microscopy, the morphological structural changes of the glomeruli and tubules in rats with chronic renal failure model caused by 5/6 nephrectomy were observed, for whom SMI was given intraporitoneally as a protecfive therapy. Results SMI could promote the recovery of injured glomeruli and tubules. Its effect was associated with inhibiting interstitial nephritis. Conclusion SMI has the protective effect on the kidneys in rats with 5/6 nephrectomy by inhibiting interstitial nephritis. |
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| Keywords: | Shenmai injection renal failure renal morphology interstitial nephritis Panax ginseng radix ophiopogonis |
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