血清C肽和糖化血红蛋白联合检测对糖尿病诊断的临床价值研究

目的探究血清C肽、糖化血红蛋白二者联合检测在糖尿病临床诊断中的临床价值。方法整理2018年1月—2019年2月期间该院内二科收治的56例糖尿病患者设为观察组,同期选择56名身体健康的老年人设为对照组。对两组进行血清C肽检测与糖化血红蛋白检测,分析两种检测方法的检测结果及临床检测价值。结果观察组的糖化血红蛋白、空腹血糖水高于对照组,观察组的血清C肽水平低于对照组。合并并发症患者的糖化血红蛋白、空腹血糖水高于无并发症患者,而合并并发症患者的血清C肽低于无并发症的患者。以上差异有统计学意义(P<0.05)。结论在糖尿病临床诊断中进行血清C肽、糖化血红蛋白检测,可显著提高诊断效果,有利于临床医师有效判断患者的病情严重程度,了解其血糖水平变化,为临床诊治提供有价值的依据。

Clinical Value of Combined Detection of Serum C-peptide and Glycosylated Hemoglobin for Diagnosis of Diabetes

Objective To investigate the clinical value of combined detection of serum C-peptide and glycated hemoglobin in the clinical diagnosis of diabetes.Methods A total of 56 patients with diabetes mellitus admitted to the hospital from January 2018 to February 2019 were enrolled in the observation group.56 healthy individuals were selected as the control group.Serum C-peptide detection and glycosylated hemoglobin were detected in both groups,and the detection results and clinical detection value of the two detection methods were analyzed.Results The glycated hemoglobin and fasting blood glucose in the observation group were higher than those in the control group.The serum C-peptide level of the observation group was lower than that of the control group.Glycated hemoglobin and fasting blood glucose were higher in patients with complications than in uncomplicated patients,and patients with complications had lower serum C-peptide than patients without complications.The above differences were statistically significant(P<0.05).Conclusion The detection of serum C-peptide and glycosylated hemoglobin in the clinical diagnosis of diabetes can significantly improve the diagnostic effect,which is helpful for clinicians to effectively judge the severity of the patient's condition and understand the changes of blood glucose level,which provides a valuable basis for clinical diagnosis and treatment.