| 二甲双胍对糖尿病足溃疡愈合的影响 |
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| 引用本文： | 辛燕,李伟,刘大龙. 二甲双胍对糖尿病足溃疡愈合的影响[J]. 糖尿病新世界, 2020, 0(2): 193-195 |
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| 作者姓名： | 辛燕 李伟 刘大龙 |
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| 作者单位： | 兰州市第一人民医院内分泌科;延安大学附属医院内分泌科;兰州市第一人民医院神经内科 |
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| 摘 要： | 二甲双胍对于糖尿病足溃疡愈合的影响做一综述,通过查阅文献发现二甲双胍通过减轻局部胰岛素抵抗、减少氧化应激、促进血管形成、减轻炎症等途径从而促进糖尿病足溃疡的愈合,但其可通过抑制角质细胞增殖而延长足溃疡的愈合。其对足溃疡的愈合影响未能达到一致。
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| 关 键 词： | 二甲双胍 糖尿病足溃疡 综述 |
Effect of Metformin on Healing of Diabetic Foot Ulcer |
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| XIN Yan,LI Wei,LIU Da-long. Effect of Metformin on Healing of Diabetic Foot Ulcer[J]. Diabetes New World, 2020, 0(2): 193-195 |
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| Authors: | XIN Yan LI Wei LIU Da-long |
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| Affiliation: | (Department of Endocrinology,Lanzhou First People's Hospital,Lanzhou,Gansu Province,730050 China;Department of Endocrinology,Affiliated Hospital of Yan'an University,Yan'an,Shanxi Province,716000 China;Department of Neurology,Lanzhou First People's Hospital,Lanzhou,Gansu Province,730050 China) |
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| Abstract: | The effect of metformin on the healing of diabetic foot ulcers is reviewed.It is found that metformin promotes the healing of diabetic foot ulcers by reducing local insulin resistance,reducing oxidative stress,promoting angiogenesis,and reducing inflammation.Inhibition of keratinocyte proliferation prolongs the healing of foot ulcers.Its effect on the healing of foot ulcers has not been consistent. |
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| Keywords: | Metformin Diabetic foot ulcer Review |
| 本文献已被 CNKI 维普 等数据库收录！ |
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