| 长链非编码RNA影响糖尿病心肌病的研究 |
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| 引用本文： | 白雨鑫,王翀,刘贵波,梁军,郭素芬,吴琦,刘瑞芳,周倩,成永霞.长链非编码RNA影响糖尿病心肌病的研究[J].糖尿病新世界,2020(1):195-198. |
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| 作者姓名： | 白雨鑫 王翀 刘贵波 梁军 郭素芬 吴琦 刘瑞芳 周倩 成永霞 |
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| 作者单位： | 牡丹江医学院第一临床医学院病理诊断中心;牡丹江医学院基础医学院解剖教研室;牡丹江医学院基础医学院组胚教研室;牡丹江医学院基础医学院病理生理学教研室 |
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| 基金项目： | 2018年黑龙江省自然基金(H2018069);2018年度黑龙江省省属高等学校基本科研业务费科研项目(2018-KYYWFMY-0078)。 |
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| 摘 要： | 随着人类科学技术的发展,人类对基因组计划的完成并对基因组的进一步研究,发现存在不编码蛋白质的RNA,其相同特征是都能从基因组上转录而来,但是不能通过翻译转化成蛋白,在RNA水平上就能发挥各自的生物学效应,这一结果产生,引起人们对于非编码RNA的研究兴趣,而又最新的研究表明,非编码RNA与糖尿病及其并发症具有一定的联系,然而合并心血管系统并发症的糖尿病患者致死率增加2倍以上。因此该文将针对非编码RNA对糖尿病心肌病的发病机制进行进一步的研究。
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| 关 键 词： | 糖尿病心肌病 发病机制 lncRNA |
Long-chain Non-coding RNA Affecting Diabetic Cardiomyopathy |
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| BAI Yu-xin,WANG Chong,LIU Gui-bo,LIANG Jun,GUO Su-fen,WU Qi,LIU Rui-fang,ZHOU Qian,CHENG Yong-xia.Long-chain Non-coding RNA Affecting Diabetic Cardiomyopathy[J].Diabetes New World,2020(1):195-198. |
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| Authors: | BAI Yu-xin WANG Chong LIU Gui-bo LIANG Jun GUO Su-fen WU Qi LIU Rui-fang ZHOU Qian CHENG Yong-xia |
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| Institution: | (Department of Pathology,First Clinical Medical College,Mudanjiang Medical College,Mudanjiang,Heilongjing Province,157000 China;Department of Anatomy,Mudanjiang Medical College,Mudanjiang,Heilongjing Province,157000 China;Department of Biochemistry,Department of Basic Medical Sciences,Mudanjiang Medical College,Mudanjiang,Heilongjing Province,157000 China;Department of Pathophysiology,Mudanjiang Medical College,Mudanjiang,Heilongjing Province,157000 China) |
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| Abstract: | Along with the development of human science and technology,human genome project completion and the further study of the genome,and found that there is no coding of RNA and protein;the same features can be transcribed from the genome,but can't translated into protein,at the RNA level,they will be able to live up to their biological effect,this results arouse people's non-coding RNA research interests,and the latest research suggests that noncoding RNA has a connection with diabetes and its complications,but combined cardiovascular complications of diabetes patient mortality rate increased by more than twice.Therefore,this paper will further study the pathogenesis of diabetic cardiomyopathy with non-coding RNA. |
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| Keywords: | Diabetic cardiomyopathy Pathogenesis lncRNA |
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