观察使用格列齐特缓释片、二甲双胍、阿卡波糖联合治疗对2型糖尿病的降糖作用和对胰岛素的影响

目的观察使用格列齐特缓释片、二甲双胍、阿卡波糖联合治疗对2型糖尿病的降糖作用和对胰岛素的影响。方法选择该院于2018年4月—2019年4月期间收治的120例2型糖尿病患者为该次研究对象,将所有患者按照治疗方案的不同分为对照组(n=60)与研究组(n=60),对照组采用二甲双胍治疗方案,研究组应用格列齐特缓释片、二甲双胍、阿卡波糖联合治疗方案,对比分析两组患者血糖水平、空腹胰岛素和胰岛素抵抗指数。结果观察组患者空腹血糖、餐后2 h血糖明显低于对照组,研究组空腹胰岛素高于对照组,同时胰岛素抵抗指数低于对照组(P<0.05)。结论针对2型糖尿病患者采用格列齐特缓释片、二甲双胍、阿卡波糖联合治疗效果尤为显著,能够有效降低患者血糖水平,提高体内胰岛素水平,同时降低胰岛素抵抗作用,临床使用价值较高。

Observation on the Hypoglycemic Effect and Insulin Effect of Type 2 Diabetes on the Combination of Glipizide Extended-release Tablets,Metformin, and Acarbose

Objective To observe the hypoglycemic effect and insulin effect of type 2 diabetes mellitus treated with glipizide sustained-release tablets,metformin,and acarbose.Methods A total of 120 patients with type 2 diabetes who were treated in our hospital from April 2018 to April 2019 were selected as the research subjects.All patients were divided into control group(n=60 cases)and study group(n=60 cases)according to different treatment plans,the control group was treated with metformin,and the study group was treated with glipizide sustained-release tablets,metformin,and acarbose.The blood glucose levels,fasting insulin,and insulin resistance index of the two groups were compared and analyzed.Results The fasting blood glucose and 2h postprandial blood glucose of the observation group were significantly lower than those of the control group.The fasting insulin of the study group was higher than that of the control group,and the insulin resistance index was lower than that of the control group(P<0.05).Conclusion The combination of Glezide extended-release tablets,metformin,and acarbose is particularly effective for patients with type 2 diabetes,which can effectively reduce blood glucose levels,increase insulin levels in the body,and reduce insulin resistance.