| 松潘乌头二萜生物碱的研究 |
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| 引用本文： | 李洪刚,李广义. 松潘乌头二萜生物碱的研究[J]. 药学学报, 1988, 23(6): 460-463 |
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| 作者姓名： | 李洪刚 李广义 |
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| 作者单位： | 甘肃省新医药学研究所 兰州(李洪刚)，中国医学科学院药物研究所 北京(李广义) |
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| 摘 要： | 甘肃省文县产的松潘乌头(Aconitum sungpanense Hand-Mazz),俗称缠绕乌头,民间用于治疗跌打损伤,风湿性关节痛等症。其化学成分尚未见报道。松潘乌头粗粉用0.5%的盐酸渗漉,通过阳离子树脂交换,经乙醚及二氯甲烷先后洗脱,乙醚部分用硅胶柱层析等
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| 关 键 词： | 松潘乌头 13,15-双去氧乌头碱 8-乙酰-14-苯甲酰查斯曼宁 查斯曼宁 它拉乌头胺 黄草乌碱甲 黄草乌碱丙 |
| 收稿时间： | 1987-08-08 |
STUDIES ON THE DITERPENOID ALKALOIDS FROM ACONITUM SUNGPANENSE HAND-MAZZ |
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| HG Li and GY Li. STUDIES ON THE DITERPENOID ALKALOIDS FROM ACONITUM SUNGPANENSE HAND-MAZZ[J]. Acta pharmaceutica Sinica, 1988, 23(6): 460-463 |
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| Authors: | HG Li and GY Li |
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| Abstract: | Six crystalline alkaloids were isolated from the roots of Aconitum sungpanense. Hand. -Mazz. Four of them were known compounds: chasmanine (Ⅰ), talatisamine (Ⅳ), vilmorrianine A (Ⅲ) and C (Ⅵ). The structures of alkaloids Ⅱ and Ⅴ were elucidated as 13, 15-dideoxyaconitine C34H47O9N, mp 167～169℃(or 112～114℃) and 8-acetyl-14-benzoylchasmaninie C34H47O3N, mp 150～152℃ respectively by spectroscopy. These two alkaloids were first found from the title plant as natural products. |
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| Keywords: | Aconitum sungpanense Hand.-Mazz. 13 15-Dideoxyaconitine 8-Acetvl-14-benzoylchasmanine Chasmanine Talatisamine Vilmorrianine A Vilmorrianine C |
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