酮咯酸氨丁三醇在子宫输卵管超声造影中的超前镇痛作用

目的探讨酮咯酸氨丁三醇在经阴道四维子宫输卵管超声造影（TVS 4D-HyCoSy）中的超前镇痛作用。 方法选取2018年5月至2019年3月于云南省第三人民医院因不孕症拟行TVS 4D-HyCoSy的患者102例。依据检查前使用镇痛药物的不同，将其分为观察组（造影前半小时肌内注射酮咯酸氨丁三醇）51例和对照组（造影前半小时肌内注射阿托品）51例，比较2组的镇痛效果及不良反应发生率。 结果观察组镇痛总有效率为96.1%（49/51），对照组总有效率为82.4%（42/51）。观察组显效3例，有效46例，无效2例；对照组有效42例，无效9例，无一例显效。观察组超前镇痛效果优于对照组（Z=-2.707，P=0.007）。观察组不良反应发生率较对照组低（3.9% vs 23.5%），差异有统计学意义（χ²=8.279，P=0.004）。 结论TVS 4D-HyCoSy前使用酮咯酸氨丁三醇超前镇痛的效果优于阿托品，值得临床推广运用。

Preemptive analgesia effect of ketorolac tromethamine in hysterosalpingo-contrast sonography

Objective To investigate the preemptive analgesia effect of ketorolac tromethamine in transvaginal four-dimensional hysterosalpingo-contrast sonography(TVS 4D-HyCoSy).Methods From May 2018 to March 2019,102 patients were scheduled to undergo TVS 4D-HyCoSy due to infertility at the Third People's Hospital of Yunnan Province.According to the different analgesics used before the test,they were divided into either an observation group(ketorolac tromethamine group;n=51)or a control group(atropine group;n=51).The analgesic effect and adverse reaction rate of the two groups were compared.Results The total effective rate of the observation group was 96.08%(49/51),and that of the control group was 82.35%(42/51).The analgesic effect of the observation group was significantly better than that of the control group(Z=-2.707,P<0.05).The rate of adverse reactions of the observation group was significantly lower than that of the control group(3.92%vs 23.53%,χ^2=8.279,P<0.05).Conclusion The analgesic effect of ketorolac tromethamine in TVS 4D-HyCoSy is better than that of atropine.