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CONGENITAL HYPOTHYROIDISM AND CHANGES IN THE ENAMEL OF DECIDUOUS TEETH
Authors:J. G. NOREN  J. ALM
Affiliation:Department of Pedodontics, Faculty of Odontology, University of Göteborg, Sweden, the Department of Dental Pathology and Operative Dentistry, Royal Dental College, Århus, Denmark, and the Department of Paediatrics, Karolinska Institute, St. Göran's Children's Hospital, Stockholm, Sweden
Abstract:ABSTRACT. Deciduous teeth from children with congenital hypothyroidism were collected and ground sections were prepared. The sections were analysed by means of polarised light and microradiography. The enamel in ground sections of deciduous teeth from children with congenital hypothyroidism showed an increase in areas with elevated pore volume distribution in both the pre- and postnatal enamel. The findings suggest that thyroid hormone influences enamel maturation. Further, alterations in enamel structure, presumably due to prenatal thyroid deficiency, were found to be more common among children with neurological abnormalities at the age of 7 to 9 years.
Keywords:Hypothyroidism    deciduous teeth    mineralisation disturbances    microradiography    polarisation microscopy
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