三地益血汤联合西药治疗ITP 36例临床观察

目的：观察三地益血汤联合西药治疗特发性血小板减少性紫癜（ITP）的临床疗效。方法：选择70例ITP患者,随机分为对照组和治疗组。2组均以胸腺肽80 mg＋5%葡萄糖（GS）250 mL静脉滴注,1次/d;参麦注射液50mL＋5%GS250mL静脉滴注,1次/d;泼尼松,1mg/（kg.d）,口服;氨肽素,5粒/次,3次/d;血小板〈30×109/L者给予环孢素A,30 mg/次,口服。治疗组在常规治疗的基础上给予自拟三地益血汤。2组均以治疗14天为1个疗程,治疗2个疗程后观察疗效。结果：总有效率治疗组为94.44%,对照组为85.29%,2组相比差异有统计学意义（P〈0.05）。2组均未见明显不良反应。结论：三地益血汤联合西药治疗ITP提高临床疗效,减少西药副作用。

Clinical Observation on SanDi YiXue Tang and Western Medicine in Treating 36 Cases of ITP

Objective： To observe clinical effects of SanDi YiXueTang and western medicine in treating idiopathic thrombocytopenic purpura （ITP）. Method： All 70 patients with ITP were randomized into control group and treatment group. Both groups received 80mg of thymic peptide and 250mL of 5% glucose through intravenous drip, once per day; 50 mL of ShenMai injection and 250 mL of 5% glucose through intravenous drip, once per day; prednisone, 1 mg/ （kg·d）, oral; ampeptide elemente, five pills once, three times per day; ciclosporin A was given to the patient whose blood platelets were less than 30×109/L, 30 mg per day, oral. Treatment group took self-design SanDi YiXueTong. For both groups one session was 14 days and curative effects were observed after two sessions. Result： Total effective rate of treatment group was 94.44%, higher than 85.29% of control group with statistical meaning（P〈0.05）. No adverse reaction occurred in both groups. Conclusion： SanDi YiXueTang combined with western medicine can improve clinical effects and reduce side effects of western medicine.