氯诺昔康联合中药舒筋洗治疗膝骨关节炎疗效分析

目的:观察氯诺昔康联合中药舒筋洗外用治疗膝骨关节炎的临床疗效。方法:80例膝骨关节炎患者,随机分为氯诺昔康组和联合治疗组,每组40例。氯诺昔康组口服氯诺昔康每次8mg,bid,连续4周;联合治疗组在氯诺昔康组基础上加用舒筋洗浸洗患处,每天2次,连续治疗4周。分别在治疗前后进行疗效评估。结果:2组对膝骨关节炎的休息痛、活动痛、关节压痛、关节肿胀、关节活动度和15m步行时间等各项指标的有效率均超过70%;与氯诺昔康组比较,联合治疗组在对关节肿胀指标的改善上有显著性差异(P <0.05)。2组均未见明显不良反应。结论:氯诺昔康联合中药外洗治疗膝关节骨关节炎效果显著,对于关节肿胀的患者尤为适用。

The Efficacy of Knee Osteoarthritis Treated by Lornoxicam and Shu-Jin-Xi Granule

To observe the efficacy of lornoxicam and ShuJinXiKeLi on patients with knee Osteoarthritis. Methods: 80 patients with knee Osteoarthritis were randomly divided into two groups. The contrast group (n=40) was receipted lornoxicam 8 mg,bid,po;and the trial group (n=40) was receipted lornoxicam 8 mg,bid,po and ShuJinXiKeLi for external application,bid. The treatment duration time of two groups were 4 weeks. Clinical efficacy were evaluated before and after treatment. Results: All index after treatment improved markedly (P <0.01) and a total effective rate of >70% were obtained in both groups. The rate of knee swelling in trial group after treatment were decreased markedly compared with contrast group (P <0.05). Conclusion: Lornoxicam and ShuJinXiKeLi are effective treatment on patients with knee Osteoarthritis.