| 体外冲击波治疗骨折延迟愈合及骨不连:动物实验及临床病例随访 |
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| 引用本文： | 邢星,冯培.体外冲击波治疗骨折延迟愈合及骨不连:动物实验及临床病例随访[J].中国组织工程研究与临床康复,2010,14(9). |
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| 作者姓名： | 邢星 冯培 |
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| 作者单位： | 齐齐哈尔市公安医院骨外科,黑龙江省齐齐哈尔市,161006 |
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| 摘 要： | 背景:体外冲击波技术是利用液电能量转换及传递原理,造成不同密度组织之间产生能量梯度差及扭拉力,从而达到治疗目的,它用于治疗泌尿系、消化系结石已成为十分成熟的技术.而将其用于骨组织,治疗骨不连、骨折延迟愈合的报道很少.目的:通过动物实验及临床验证试验,观察体外冲击波治疗骨不连及骨折延迟愈合的疗效果.方法:采用冲击波通过体外聚焦作用于骨组织,了解体外冲击波对骨膜组织代谢的影响,通过动物实验,观察骨膜组织体外培养H~3-TdR掺入放射性自显影结果.临床验证部分通过体外冲击波治疗骨不连16例及骨折延迟愈合16例,观察其冲击治疗后的随访结果.结果与结论:动物实验结果表明,冲击1,2周实验侧骨膜组织H~3-TdR标记率明显高于对照侧(P＜0.05～0.01),说明实验侧骨膜成骨有丝分裂明显增强,骨膜成骨作用增强.临床验证结果表明,治疗后16周,16例延迟愈合均愈合;16例骨不连患者中13例愈合,另3例也有明显骨痂形成.所有病例冲击治疗后均无不良事件发生.提示冲击波治疗各种类型的骨不连及骨折延迟愈合效果可靠.
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| 关 键 词： | 体外冲击波 骨折 延迟愈合 骨不连 动物实验 临床验证 |
Extracorporeal shock wave therapy for nonunion or delayed osseous union:Animal experiment and clinical follow-up |
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| Xing Xing,Feng Pei.Extracorporeal shock wave therapy for nonunion or delayed osseous union:Animal experiment and clinical follow-up[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2010,14(9). |
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| Authors: | Xing Xing Feng Pei |
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| Institution: | Xing Xing,Feng Pei Department of Orthopaedics Surgery,Public Security Hospital of Qiqihaer City,Qiqihaer 161006,Heilongjiang Province,China |
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| Abstract: | BACKGROUND:Extracorporeal shock wave(ESW) therapy is using principles of liquid-electric conversion and transfer to produce energy gradient difference and torsional tension in tissues with varied density.It is a matured technique in treating urinary and digestive system calculosis.However,the applications of ESW in treating nonunion or delayed osseous union are few.OBJECTIVE:To explore the therapeutic effects of ESW in treating nonunion or delayed osseous union by animal experiment and clinical verification... |
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