实时灰阶超声造影在肝肿瘤诊断中的价值

目的:评价实时灰阶超声造影在肝肿瘤诊断中的价值.方法:利用实时灰阶超声造影观察50例54个肝实质性肿块的动态增强表现作出造影诊断,并与病理对照.结果:除2例少血供胃肠道肝转移癌、1例手术后疤痕及1例炎性假瘤未见增强外,其余肿块均有不同程度的增强.肝恶性肿块早期动脉相强化,消失较快;肝血管瘤(HCH)增强速度较慢,呈周边强化;肝局灶性结节性增生(FNH)早期动脉相强化,但持续时间较长;肝硬化结节与肝实质呈同步强化.如以动脉相增强呈高回声而门脉相消失呈低回声考虑为肝恶性肿瘤,则本组超声造影诊断肝恶性肿瘤的敏感性、特异性及准确性分别为91.7%(33/36),100%(18/18)和94.4%(51/54).结论:实时灰阶超声造影可得到丰富的肝肿瘤供血及血流灌注信息,对肝肿瘤的诊断、鉴别诊断有重要的临床应用价值.

Diagnostic value of real-time grey-scale contrast-enhanced ultrasonography for hepatic tumors

AIM:To investigate the diagnostic value of new contrast agent SonoVue and real-time gray-scale contrast-enhanced ultrasonography for hepatic tumors. METHODS:We used color Doppler flow imag- ing,power Doppler imaging and real-time gray- scale contrast-enhanced ultrasonography to ex- amine 50 patients with 54 solid hepatic lesions. All lesions were confirmed by pathology follow- ing surgery or needle biopsy. RESULTS:Fifty lesions were variously enhanced on gray-scale ultrasonography after injection of SonoVue,except for 2 cases with liver metastases, 1 of which had an operational scar and the other inflammatory pseudotumor of the liver.The sensitivity,specificity and accuracy of contrast- enhanced ultrasonography for the diagnosis of hepatic malignant tumor were 91.7% (33/36), 100% (18/18) and 94.4% (51/54),respectively. CONCLUSION:Real-time gray-scale contrast- enhanced ultrasonography is useful for diagnos- ing and discriminating hepatic tumors.