Serum alpha-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia |
| |
Authors: | Clericuzio Carol L Chen Emily McNeil Dawn Elizabeth O'Connor Timothy Zackai Elaine H Medne Livija Tomlinson Gail DeBaun Michael |
| |
Affiliation: | Department of Pediatrics, University of New Mexico, ACC-3, Albuquerque, NM 87131, USA. |
| |
Abstract: | An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum alpha-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma. |
| |
Keywords: | AFP, α-fetoprotein HBL, Hepatoblastoma AGA, Appropriate for gestational age HH, Hemihyperplasia BWS, Beckwith-Wiedemann syndrome LGA, Large for gestational age CT, Computed tomography US, Ultrasound |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|