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Anaphylactic reaction to isosulfan blue used for sentinel node biopsy: case report and literature review
Authors:Efron Philip  Knudsen Ellen  Hirshorn Stephen  Copeland Edward M
Affiliation:Departments of Surgery and; Anesthesia, Shands Hospital, University of Florida, Gainesville, Florida
Abstract:Isosulfan blue is a commonly used agent in the detection of sentinel lymph nodes during cancer surgery. Similar to any drug, it is possible to have an allergic reaction to this increasingly popular chemical during breast cancer operations. We present one case of anaphylactic shock in response to injection of isosulfan blue for the purpose of localizing the sentinel node and review the medical literature. A thorough knowledge of possible isosulfan blue side effects, including their presentation and subsequent therapy, is essential for the modern breast surgeon.
Keywords:anaphylaxis    breast adenocarcinoma    breast cancer    isosulfan blue    modified radical mastectomy    sentinel lymph node
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