依达拉奉联合苦碟子对急性脑梗死C反应蛋白和IL-6的影响

目的 探讨依达拉奉联合苦碟子对急性脑梗死患者血浆C反应蛋白(CRP)和白细胞介素-6(IL-6)水平的影响.方法 92例急性脑梗死随机分为依达拉奉注射液联合苦碟子注射液治疗组(治疗组)和苦碟子注射液治疗组(对照组),治疗前和治疗2个疗程后测定血浆CRP和IL-6水平.结果 两组患者治疗后,对照组和治疗组的CRP较治疗前分别地降低18.8%、46.7%,IL-6浓度较治疗前分别降低12.7%和9.6%,经统计学处理均有统计学意义(P<0.05或P<0.01).结论 依达拉奉联合应用苦碟子可通过降低CRP及IL-6水平来发挥保护脑组织作用.

Effect of Edaravone with Kudiezi Injection on Plasma C - reactive Protein and Interleukin - 6 in Acute Cerebral Infarction

Objective To investigate the effect of edaravone with Kudiezi(ixeri sonhifolia) injection on plasma C- reactive protein (CRP) and interleukin - 6(IL - 6) in patients(pts) with acute cerebral infarction(ACI). Methods Ninety - two pts with ACI were randomly divided into two groups:Treatment group treated by edaravone with Kudiezi injection and control group treated by Kudiezi injection. The levels of plasma CRP and IL - 6 were determined before and after treatment. Results After treatment, the levels of plasma CRP in treatment group and control group were decreased by 18.8% and 46.72%,respectively,and plasma IL- 6 levels were decreased by 12.7% and 9.6% respectively(P<0.05 or P<0.01). Conclasion Edaravone with Kudiezi injection had protective effect on brain tissue by lowering plasma CRP and IL - 6 levels.