白头翁汤灌肠联合西药治疗慢性结肠炎随机平行对照研究

目的]观察白头翁汤灌肠联合西药治疗慢性结肠炎疗效。方法]使用随机平行对照方法,将78例住院患者按随机数字表方法随机分为两组。对照组33例柳氮磺胺吡啶,口服,1.2g/次,每隔7.5h服用一次,按患者情况调整用量。治疗组45例白头翁汤灌肠(白头翁、黄芪各28g,秦皮、炮姜炭、黄连、木香、黄柏各5g,丹皮、大黄炭、当归、生薏仁各7g,虎杖、山楂炭、银花炭各12g),煎药120mL,患者睡前排空大便,用注射器和导管将药剂注入直肠,1次/d。西药治疗同对照组,连续治疗1周为1疗程。观测临床症状、不良反应。连续治疗3个疗程,判定疗效。结果]治疗组显效31例,有效13例,无效1例,总有效率97.80%,不良反应率4.40%。对照组显效17例,有效8例,无效8例,总有效率75.80%,不良反应率15.20%。治疗组疗效优于对照组(P<0.05),不良反应率治疗组低于对照组(P<0.05)。结论]白头翁汤灌肠联合西药治疗慢性结肠炎疗效满意,不良反应率低,值得推广。

Treatment of Chronic Colitis Randomized Controlled Trial of Pulsatilla Decoction Combined with Western Medicine

Objective]Observation of Pulsatilla decoction combined with western medicine in treatment of chronic colitis.Methods] The use of a randomized controlled method,78 patients according to the random number table method were randomly divided into two groups.A control group of 33 cases of sulfasalazine,oral,1.2g /,every 7.5h to take time,amount according to the patient specific health and condition adjustment.The treatment group of 45 cases of Pulsatilla Decoction enema,medicinal Pulsatilla chinensis,Astragalus 28g,cortex Fraxini,blast-fried ginger,Rhizoma Coptidis,Radix Aucklandiae,treats each 5 grams,Cortex Moutan,angelica,rhubarb charcoal,raw barley 7g,giant knotweed,hawthorn carbon,Yinhua carbon 12g.Method 120mL patients before emptying,stool,the syringe and catheter in patients with rectal agent injection,1 / d.Western medicine treatment with the control group,continuous treatment for 1 weeks as 1 course of treatment.Observation of clinical symptoms.Results] The treatment group 31 cases,effective 13 cases,invalid 1 cases,the total efficiency of 97.80%,the adverse reaction rate of 4.40%.The control group 17 cases markedly effective,effective 8 cases,invalid 8 cases,the total efficiency of 75.80%,the adverse reaction rate of 15.20%.The efficacy of the treatment group than in control group(P < 0.05),the adverse reaction rate of treatment group was lower than that of control group(P < 0.05).Conclusion]Pulsatilla decoction combined with western medicine in treatment of chronic colitis curative effect,low rate of adverse reactions,is worthy of promotion.