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The results of an mtDNA study of 1200 inhabitants of a German village in comparison to other Caucasian databases and its relevance for forensic casework |
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| Authors: | H Pfeiffer P Forster C Ortmann B Brinkmann |
| Institution: | (1) Institute of Legal Medicine, University of Münster, Von Esmarch-Strasse 62, 48149 Münster, Germany e-mail: pfeiffh@uni-muenster.de; Fax: +49-251-8355158, DE;(2) McDonald Institute for Archaeological Research, University of Cambridge, Downing Street, Cambridge, CB2 3ER, UK, HM |
| Abstract: | Mitochondrial DNA control region sequences were determined in 1200 male volunteers from one village area of Lower Saxony for the hypervariable region 1 (HV1). The 154 variable positions found resulted in 460 different haplotypes with a haplotype diversity value of 0.98165. The number of different haplotypes showed a nearly linear increase with the number of individuals typed. The haplotype diversity approached saturation level at a value of approximately 0.981 after typing 400 individuals. Furthermore, the number of different haplotypes and the haplotype diversity were calculated for four short amplicons of HV1 in order to establish the most variable section with a high efficiency for forensic casework. Received: 29 January 2000 / Accepted: 24 April 2000 |
| Keywords: | Mitochondrial DNA Hypervariable region 1 Forensic science |
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