乳腺手术患者围手术期抗生素应用分析

目的了解乳腺手术患者围手术期抗生素应用现状及合理性。方法对2010年1～12月335例乳腺手术患者围手术期抗生素应用进行回顾性调查。结果围手术期抗生素使用率为92.24%。围手术期抗生素主要以第一代头孢菌素类、喹诺酮类为主。第一代头孢菌素类使用率最高,为89.76%。二联用药应用率为1.62%,以单用为主。预防用药时机合理率为9.71%,术后用药时间普遍偏长且给药方式不尽合理。结论乳腺科围手术期抗菌药应用存在不合理现象,应建立有效的监督管理机制。

Analysis on antimicrobial administration on breast surgery during perioperative period

Objective To analyze the usage of antimicrobials in perioperative patients on breast surgery and to evaluate the rationality of use. Methods Retrospective analysis of the use of antibacterial in 335 patients discharged from the breast surgery in the hospital during the period January 2010-December 2010 was made. Results 92.24% patients received antimicrobials during perioperative period. The proportion using the first generation cephalosporins and quinolones antimicrobials was high. The first generation cephalosporins was the most commonly used drug （89.76%）. The rate of two combined administration of antimicrobials was 1.62%. The use time of antimicrobials was irrational with a high rate. Reasonable opportunity to prevent drug use was 9.71%, Inappropriate use was common with continuation and route of administration of antibiotics. Conclusion The prophylactic application of antimicrobials for perioperative period on the breast surgery has some unreasonable phe- nomenon. So the effective surveillance management mechanism should be established.