我院159例药品不良反应报告分析

目的 探讨该院药物不良反应（ADR）的发生因素、一般规律及特征,为临床合理、安全用药提供参考.方法 对2010年收集整理的159例ADR报告进行回顾性分析,结合Excel电子表格和手工筛选,按患者年龄、性别、药物种类、给药途径、ADR临床表现进行统计分析.结果 由抗菌药物导致的ADR最多,共69例占43.40%;静脉滴注方式引起ADR 99例占62.26%.ADR临床表现以皮肤及其附件损害最普遍,共81例占50.94%.结论 临床应重视ADR报告和监测工作,特别应注意观察老年人用药过程,同时合理使用抗生素,避免或减少ADR的重复发生.

Analysis on 159 Cases Reports of Adverse Drug Reaction in Our Hospital

Objective To explore hospital occurrence factors, and characteristics of the general rules of adverse drug reaction （ADR） for clinical reasonable and safe drug administration. Methods 159 cases of ADR reports in he hospital in 2010 were collected and analyzed retrospectively, with Excel spreadsheets and manual screening were used to analyzed of age, gender, drug type, route of administration and ADR clinical manifestations. Results Most ADR was caused by the antibiotics up to a total of 69 cases（43.40% ） ; 99 cases of ADR caused by intravenous infusion, accounting for 62.25%. Common clinical manifestations of ADR were damage to skin and its appendages,which presented in a total of 81 cases（50.94% ）. Conclusion Clinical attention should be paid on ADR reporting and monitoring, in particular, observing the process of older drugs, and rational use of antibiotics were needed to prevent or reduce the recurrence of ADR.