| 人参培养细胞多糖与人参多糖的免疫作用比较 |
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| 引用本文： | 人参培养细胞多糖与人参多糖的免疫作用比较[J]. 中国药科大学学报, 1989, (4): 216-218. |
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| 作者姓名： | 李佩珍 杭秉茜 丁家宜 |
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| 作者单位： | 中国医科大学中药药理教研室(李佩珍，杭秉茜)，中国医科大学植物组织培养研究室(丁家宜) |
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| 摘 要： | 人参培养细胞的多糖可明显增加小鼠脾重量,而对小鼠胸腺重量影响不大。能显著增强小鼠碳粒廓清速率,明显促进小鼠溶血素抗体的活性,提高正常小鼠血清IgG含量,对SRBC所致迟发型超敏反应有促进作用,而对小鼠的移植物抗宿主反应(GVHR)影响不大。与栽培人参多糖的作用无明显差异。
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| 关 键 词： | 人参多糖 人参培养细胞多糖 碳粒廓清 溶血素 IgG 迟发型超敏反应 移植物抗宿主反应 |
COMPARISON OF IMMUNE FUNCTION BETWEEN POLYSACCHRIDES FROM TISSUE CULTURE OF PANAX GINSENG AND FROM GINSENG ROOT |
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| COMPARISON OF IMMUNE FUNCTION BETWEEN POLYSACCHRIDES FROM TISSUE CULTURE OF PANAX GINSENG AND FROM GINSENG ROOT[J]. Journal of China Pharmaceutical University, 1989, (4): 216-218. |
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| Authors: | Li Peizheng Hang Bingqian Ding Jiayi |
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| Affiliation: | Li Peizheng,Hang Bingqian and Ding Jiayi Department of Pharmacology of Chinese Materia Medica |
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| Abstract: | The effect of polysaccharide from tissue culture of Panax ginseng on immune function was studied, and compared with the polysaccharide from ginseng root.Both polysaccharides iv 20mg / kg, 40mg / kg(three times at interval of 3 days)caused marked increase of weight of spleen and enhanced the clearance rate of iv charcoal particles in mice.The two polysaccharides also significantly promoted the production of serum specific antibody hemolysins in mice and the level of IgG.They also enhanced DTH of footpad induced by SRBC in mice.But they had no effect on GVHR in mice.It is suggested that the two polysaccharides have the same effect on immune functions. |
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| Keywords: | Polysaccharide of Panax ginseng Polysaccharide from tissue culture of Panax ginseng Charcoal clearance Hemolysin IgG DTH GVHR |
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