复方多黏菌素B软膏治疗寻常痤疮临床疗效观察

目的观察复方多黏菌素B软膏治疗寻常痤疮的疗效及安全性。方法将156例寻常痤疮患者分为两组,试验组外用复方多黏菌素B软膏每日2次,对照组外用5%过氧苯甲酰凝胶每日2次,疗程均为4周。结果试验组患者经治疗4周后皮损数量明显较治疗前减少,与对照组相比差异有统计学意义(P<0.05);皮损消退显效率两组无明显差异(P>0.05);不良反应发生率试验组低于对照组(P<0.05)。结论复方多黏菌素B软膏治疗Ⅰ、Ⅱ级寻常痤疮有效,且不良反应少。

Clinical study on treatment of acne vulgaris with compound polymycin B ointment

Objective To evaluate the effect and safety of compound polymycin B cream in treating acne vulgaris. Methods 156 ache vulgaris patients （I, Ⅱ stage） were randomly divided into two groups, the treatment group were topically applied compound polymycin B cream and control group were topically applied 5% benzoylperoxide gel. The course of treatment was 4 weeks. Results The results showed the difference of effective rates between two groups was not statistically significant （P〉0.05）, the side effects in the compound polymycin B cream treatment group was less than the control group （P〈0.05）. Conclusion The study indicates that, comparing with 5% benzoylperoxide gel, compound polymycin B cream topical treatment for acne vulgaris I, II stagestage is effective and safer.