| 姜黄素剂型的研究进展 |
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| 引用本文： | 林媚,王小玲,黄艳,李煌,吴必希. 姜黄素剂型的研究进展[J]. 光明中医, 2011, 26(11): 2376-2379. DOI: 10.3969/j.issn.1003-8914.2011.11.135 |
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| 作者姓名： | 林媚 王小玲 黄艳 李煌 吴必希 |
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| 作者单位： | 福建医科大学药学院药物化学系,福州,350004 |
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| 基金项目： | 福建省科技厅青年人才项目(No.2008F3049); 福建医科大学创新性实验项目(No.C09038) |
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| 摘 要： | 姜黄素是从姜黄中提取的一种植物多酚,具有抗癌等多种药理活性,且毒性较低,是很具有开发前景的药物。但是姜黄素在体外容易被氧化;在体内生物利用度低,研究合适的剂型是克服这些缺点的重要途径之一,本文着重介绍了微球、微乳、脂质体、
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| 关 键 词： | 姜黄素 剂型 稳定性 生物利用度 |
The Study of Advances on Dosage Form of Curcumin |
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| Lin Mei Wang Xiaoling Huang Yan,et al.. The Study of Advances on Dosage Form of Curcumin[J]. Journal of Traditional Chinese Medicine, 2011, 26(11): 2376-2379. DOI: 10.3969/j.issn.1003-8914.2011.11.135 |
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| Authors: | Lin Mei Wang Xiaoling Huang Yan et al. |
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| Affiliation: | Lin Mei Wang Xiaoling Huang Yan,et al.(Department of Medicinal Chemistry,School of Pharmacy,Fujian Medical University,Fuzhou 350004,China) |
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| Abstract: | Curcumin is a kind of phenolic substances extracted from Curcuma longa.It has widely pharmacological activities such as anti cancer effect and low-side effect,so it a kind of drug owning bright prospect.However,it is easily to be oxidized in vitro and has low bioavailability in vivo.To research a suitable dosage form for curcumin is an effective way to overcome these weaknesses.This article introduced the newly development of dosage forms of curcumin mainly about microsphere,microemulsion,liposome,dropping ... |
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| Keywords: | Curcumin dosage form stability bioavailability |
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