| 旋光法和紫外分光光度法测定卡地滴眼液含量 |
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| 引用本文： | 李伊庆,王海燕,姜宗文.旋光法和紫外分光光度法测定卡地滴眼液含量[J].药学实践杂志,2002,20(3):174-176. |
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| 作者姓名： | 李伊庆 王海燕 姜宗文 |
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| 作者单位： | 解放军第461医院,长春,130021 |
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| 摘 要： | 目的 :建立卡地滴眼液的含量测定方法。方法 :用旋光法测定卡地滴眼液中卡那霉素的含量 ,用紫外分光光度法测定卡地滴眼液中地塞米松磷酸钠的含量。结果 :在 1.0～ 5 .0mg·ml-1范围内旋光度与卡那霉素的浓度呈线性关系 (r =0 .9999) ,回收率平均为 99.3% ,RSD =0 .4 0 % (n =5 ) ;在 6～ 2 1μg·ml-1范围内吸收度与地塞米松磷酸钠的浓度呈线性关系 (r =0 .9998,n =6 ) ,回收率平均为 99.2 % ,RSD =0 .2 0 % (n =5 )。结论 :本法简便、快速、准确 ,适用于医院制剂的快速检验。
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| 关 键 词： | 紫外分光光度法 旋光法 卡那霉素 地塞米松磷酸钠 滴眼液 |
| 文章编号： | 1006-0111(2002)03-0174-03 |
| 收稿时间： | 2001/7/19 0:00:00 |
Assay of kanamycin and dexamethson in DICA eye drops by polarmetric analysis and ultraviolet specyrophotometry |
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| Li Yi-qing,WANG Hai-yan and JIANG Zong-wen.Assay of kanamycin and dexamethson in DICA eye drops by polarmetric analysis and ultraviolet specyrophotometry[J].The Journal of Pharmaceutical Practice,2002,20(3):174-176. |
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| Authors: | Li Yi-qing WANG Hai-yan and JIANG Zong-wen |
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| Institution: | No.461 Hospital of PLA, Changchun 130021, China;No.461 Hospital of PLA, Changchun 130021, China;No.461 Hospital of PLA, Changchun 130021, China |
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| Abstract: | OBJECTIVE:To establish a methed for determining the concentration of kanamycin and dexamethson in DICA eye drops.METHED: The concentration of kanamycin was determined by polarmetric analysis,ultraviolet specyrophotometry was employed for determination of dexamethson sodium phosphate. RESUITS:The average recovery of kanamycin was 99.3%,RSD=0.40%(n=5);the average recovery of dexamethson sodium phosphate was 99.2%,RSD=0.20%(n=5).CONCLUSION:It is a simple method for the quantitative analysis of compound preperation. |
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| Keywords: | polarmetric analysis ultraviolet specyrophotometry kanamycin dexamethson sodium phosphate eye drops |
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