Structural and functional changes in the brain of rats with different behavioral types at later stages of circulatory hypoxia |
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| Authors: | N I Artyukhina K Yu Sarkisova |
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| Institution: | (1) Laboratory of Central Nervous System Morphology, Group of Experimental Pathology and Therapy of Higher Nervous Activity, Institute of Higher Nervous Activity and Neurophysiology, the Russian Academy of Sciences, Moscow |
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| Abstract: | Structural changes in the brain were studied at later (one and three months) stages of cerebral hypoxia caused by occlusion
of the common carotid arteries, which were indicative of the development of recovery and destructive processes. Brain ultrastructure
was found to be better preserved in rats with an active type of behavior one month after the onset of ischemia than in rats
of the other groups; motor activity was restored to the baseline level, thus demonstrating a higher rate of recovery processes.
Significant ultrastructural damage to the brain at the same stage of ischemia was observed in rats with a passive type of
behavior (especially in rats of the middle group), while motor activity was increased.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N
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11, pp. 529–534, November, 1994
Presented by P. V. Simonov, Member of the Russian Academy of Sciences |
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| Keywords: | Circulatory cerebral hypoxia behavioral type brain neurons neuroglia synapses blood vessels |
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