老年女性乳腺癌166例临床分析

目的 探讨老年女性乳腺癌的手术效果.方法对1989年8月至2004年8月收治的166例老年女性乳腺癌患者的临床资料进行回顾性分析.结果166例中,改良根治术98例（59.0%）,根治术21例（12.7%）,全乳房切除术29例（17.5%）,肿瘤局部切除术18例（10.8%）.术后化疗126例,放疗12例,内分泌治疗73例.术后并发症发生率为10.8%,无手术死亡.术后3年和5年生存率分别为82.2%和65.2%.结论老年人乳腺癌采用手术及综合治疗可以取得满意的临床疗效,不同病情的患者应用不同的术式,老年并非是手术禁忌证;同时要内外科配合,重视并处理好并存症和术后并发症.

Clinical analysis of 166 aged women with breast cancer

Objective To evaluate the effect of operation on aged women with breast cancer. Methods The clinical data of the 166 patients recruited from 1989 to 2004 were retrospectively analyzed. Results One hundred and sixty six patients were all treated by operation. The modified radical mastectomy was performed in 98 cases(59.0%), radical masteetomy in 21 cases(12.7%), mastectomy in 29 cases (17.5%), palliative operation in 18 cases (10.8%). After operation, one hundred and twenty six patients received chemotherapy, twelve radiotherapy and 73 endocrine therapy. The rates of postoperative complications were 10.8%, no patients died during operation. The overall postoperative 3-and 5-year survival rates were 82.2% and 65.2% respectively. Conclusions The effect of surgical treatment and its combination with other adjunct therapies is satisfactory for aged women with breast cancer. Different types of operations should be performed for different patients. Ageing is not a contraindication of the operation. Surgery should be combined with medical therapy to reduce the concomitant diseases and postoperative complications.