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Cellular fibronectin on intraocular lenses explanted from patients
Authors:S. Saika  S. Kobata  O. Yamanaka  A. Yamanaka  K. Okubo  T. Oka  M. Hosomi  Y. Kano  S. Ohmi  S. Uenoyama  M. Tamura  R. Kanagawa  K. Uenoyama
Affiliation:(1) Department of Ophthalmology, Wakayama Medical College, 7-Bancho 27, 640 Wakayama, Japan;(2) Department of Ophthalmology, Kobe Kaisei Hospital, 3-11-15, Shinohara-Kitamachi, Nada-Ku, 675 Kobe, Japan
Abstract:We investigated the origin of fibronectin (FN) on five posterior and four anterior chamber explanted intraocular lenses (IOLs) using immunohistochemical methods. Cellular deposits (assumed to be macrophages) and fibrous or membrane-like proteinaceous deposits on the IOLs showed immunoreactivity to an antibody against cellular FN. These proteinaceous deposits were believed to be products of the cells that adhered to the IOLs.
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