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乳腺癌患者雌激素受体检测的临床意义
引用本文:邹天宁,汤学良,张勇. 乳腺癌患者雌激素受体检测的临床意义[J]. 云南医药, 2000, 0(3)
作者姓名:邹天宁  汤学良  张勇
作者单位:云南省肿瘤医院乳腺病科!云南昆明650106
摘    要:目的 探讨雌激素受体 (ER)对乳腺癌患者预后的影响。方法 对 1993年 1月~ 1998年 8月间经手术治疗的 2 85例乳腺癌患者 ,用免疫组织化学法检测其乳腺标本的ER状况。结果  2 85例乳腺癌ER检测阳性率为 6 8 0 7% ,同期伴腋窝淋巴结转移的乳腺癌 188例的ER阳性率为 6 6 49% ,二者无显著差异 (P <0 0 5 )。术后发生复发转移 11例 ,ER阴性组发生复发转移多于阳性组 ,且易转移至内脏 ,ER阳性和阴性组的复发转移率分别为 1 5 5 %和 8 79%。结论 乳腺癌的ER状况是影响预后的重要因素 ,当ER阴性时 ,应积极施行化学药物治疗以提高疗效

关 键 词:乳腺癌  腋淋巴结  雌激素受体  预后

Clinical value of examination of estrogen receptor in breast cancer.
Zou Tianning,Tang Xueliang,Zhang Yong. Breast Department,Yunnan Tumor Hospital,Kunming. Clinical value of examination of estrogen receptor in breast cancer.[J]. Medicine and Pharmacy of Yunnan, 2000, 0(3)
Authors:Zou Tianning  Tang Xueliang  Zhang Yong. Breast Department  Yunnan Tumor Hospital  Kunming
Abstract:Objective To evaluate the influence of estrogen receptor (ER)status on prognosis of breast cancer patients. Methods The ER status was examined by means of immunohistochemistry in 285 breast cancer patients.Results The ER positive rate of 285 breast cancer patients is 68 07% vs 66 49% in 188 patients with positive axillary lymphnodes (P>0 05).The metastasis and recurrence was in 11 cases, and the metastasis of ER negative group was more than ER positive group. The metastasis and recurrence rate of ER negative group and ER positive group was 8 79% and 1 55% respectively. Conclusions The ER status of breast cancer is an important factor for prognosis.
Keywords:Breast cancer Estrogen receptor
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