4β-Hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin |
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Authors: | Ulf Diczfalusy,Kajsa P. Kanebratt,Eva Bredberg,Tommy B. Andersson,Ylva Bö ttiger,& Leif Bertilsson |
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Affiliation: | Divisions of Clinical Chemistry and Clinical Pharmacology, Department of Laboratory Medicine at Karolinska Institutet, Karolinska University Hospital, Huddinge,;Department of Clinical Pharmacology &DMPK, AstraZeneca R&D Mölndal and;Section of Pharmacogenetics, Department of Physiology and Pharmacology at Karolinska Institutet, Stockholm, Sweden |
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Abstract: | |
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Keywords: | 4β-hydroxycholesterol CYP3A4 CYP3A5 rifampicin |
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