聚焦超声与低温等离子治疗后兔鼻黏膜形态学分析

目的 观察聚焦超声与低温等离子对鼻黏膜形态学的影响程度及意义.方法 运用聚焦超声技术,在设定的剂量参数下对兔鼻甲进行直线扫描;运用低温等离子射频消融术对兔鼻甲进行处理,在1个月及3个月后对两种方法处理后兔鼻甲切片及正常兔鼻甲切片进行对比观察,通过大体形态、光镜下观察对两种治疗方法兔鼻黏膜组织形态学的改变进行比较.结果 两种方法处理后1个月及3个月后兔鼻甲在外观和色泽无明显改变,光镜下显示兔鼻黏膜上皮层完整;运用低温等离子射频消融术处理后兔鼻甲外观较正常缩小,色泽灰白,且有分泌物存在,光镜下显示兔鼻黏膜上皮层断裂,部分切片上皮层完全消失.结论 在设定参数下聚焦超声可不破坏鼻黏膜上皮,可使鼻黏膜黏液纤毛系统功能得以完全保留.

The Analysis of Morphology After the Treatment of Rabbit's Nasal Mucosa with High Intensity Focused Ultrasound and Low-temperature Radiofrequency Plasma Ablation

Objective To observe the influence degree of morphology after treating the rabbit's nasal muco-sa with focused ultrasound technology.Methods By using the High Intensity Focused Ultrasound,a straight line scan for a rabbit's turbinate under the certain dose parametem had been done.And then the rabbit's turbinate was treated with low temperature plasma radiofrequency ablation.A comparison test after one month and three months was carried out.A comparison between the changes of rabbit mucosa morphological of the two kinds of treatment methods through general morphology and light microscopy observation had been taken.Results The experimental results showed that there were no significant changes in appearance and color between the use of focused ultrasound treatment of rabbit's inferior turbinate and scan the rabbit's inferior turbinate under certain dose parametem after one month and three months later.Under the lisht microscope showed a complete rabbit nasal epithelium.And after the treatment by using low-temperature plasma mdiofrequeney ablation instrument,the rabbit's turbinate became narrow,gray in color and there were some secretions compared witk normal rabbit's turbinate.Under the light microscopy,the rabbit nasal epi-thelium showed broken and part of the conical slices completely disappeared.Conclusion Under certain parameters,the focused ultrasonic energy could not undermine the nasal epithelium;thereby the function of mucociliary system is fully retained