99Tcm-MDP全身骨显像联合SPECT/CT诊断骨外肿瘤

目的 观察⁹⁹Tc^m-亚甲基二磷酸盐（MDP）全身骨显像联合SPECT/CT诊断骨外肿瘤的价值。方法 回顾性分析68例骨外肿瘤患者94处病灶，观察其全身骨显像及SPECT/CT表现，并分析二者联合诊断效能。结果 单纯全身骨显像准确诊断52处骨外肿瘤，准确率55.32%（52/94）；其余42处病灶中，35处（35/94，37.23%）因影像学表现与骨骼存在重叠而误诊为转移性骨肿瘤，7处（7/94，7.45%）因病灶⁹⁹Tc^m-MDP摄取低于邻近骨骼而致漏诊。全身骨显像联合SPECT/CT诊断全部94处骨外肿瘤，准确率100%（94/94）。94处病灶中，49处接受病理学检查，其中33处（33/49，67.35%）病灶内见粗大钙化、9处（9/49，18.37%）见细微钙化；CT检出61处（61/94，64.89%）钙化，未显示9处细微钙化。结论 ⁹⁹Tc^m-MDP全身骨显像联合SPECT/CT可提高诊断骨外肿瘤的准确性。

99Tcm-MDP whole-body bone imaging combined with SPECT/CT for diagnosis of extraosseous tumors

Objective To observe the value of ⁹⁹Tc^m-labelled methylene diphosphonate (⁹⁹Tc^m-MDP) whole-body bone imaging combining with SPECT/CT for diagnosis of extraosseous tumors. Methods A total of 94 lesions in 68 patients with extraosseous tumors were enrolled. The whole-body bone imaging and SPECT/CT manifestations of lesions were retrospectively analyzed, and the combining diagnostic efficacy was analyzed. Results The accuracy of whole-body bone imaging for diagnosis of extraosseous tumors was 55.32% (52/94). Among the rest 42 lesions, 35 (35/94, 37.23%) were misdiagnosed as metastatic bone tumors due to overlapping imaging findings with bones, while 7 (7/94, 7.45%) were misdiagnosed due to lower uptake of ⁹⁹Tc^m-MDP than adjacent bones. The accuracy of whole-body bone imaging combining with SPECT/CT for diagnosis of extraosseous tumors was 100% (94/94). Pathological examination of 49 lesions were performed, among which coarse calcifications were detected in 33 lesions (33/49, 67.35%) and fine calcifications in 9 (9/49, 18.37%) lesions. CT showed intratumoral calcifications in 61 lesions (61/94, 64.89%), not including the above 9 fine calcifications. Conclusion ⁹⁹Tc^m-MDP whole body bone imaging combining with SPECT/CT could improve the accuracy of diagnosing extraosseous tumors.