| 弥漫性大B细胞淋巴瘤t(14;18)易位和c-myc基因重排研究进展 |
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| 引用本文： | 张宏伟,程牛亮. 弥漫性大B细胞淋巴瘤t(14;18)易位和c-myc基因重排研究进展[J]. 白血病．淋巴瘤, 2009, 18(10): 630-633. DOI: 10.3760/cma.j.issn.1009-9921.2009.10.018 |
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| 作者姓名： | 张宏伟 程牛亮 |
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| 作者单位： | 山西医科大学生物化学与分子生物学教研室,太原,030001;山西医科大学生物化学与分子生物学教研室,太原,030001 |
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| 摘 要： | 弥漫性大B细胞淋巴瘤（DLBCL）是一组B淋巴细胞来源最常见的、且具有异质性的非霍奇金淋巴瘤（NHL）。就DLBCL中t(14;18)易位和c-myc基因重排及其诊断分型、治疗和预后评价方面的最新研究进展进行综述。
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| 关 键 词： | 淋巴瘤 非霍奇金 弥漫型 基因重排 研究 |
| 收稿时间： | 2009-05-13; |
Progress of t (14;18) transiocation and c-myc gene rearrangement in diffuse large B-cell lymphoma |
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| ZHANG Hong-wei,CHENG Niu-liang. Progress of t (14;18) transiocation and c-myc gene rearrangement in diffuse large B-cell lymphoma[J]. Journal of Leukemia & Lymphoma, 2009, 18(10): 630-633. DOI: 10.3760/cma.j.issn.1009-9921.2009.10.018 |
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| Authors: | ZHANG Hong-wei CHENG Niu-liang |
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| Abstract: | Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of tumors composed of large B cells. It is the most common type of non-Hodgkin lymphoma. As its variety of clinical, morphological and genetic characters, the classification and prognosis are still debated. This article aims to elucidate t(14;18) translocation and c-myc gene rearrangement is of great significance to the clinical diagnosis, classification, treatment and prognosis of DLBCL. |
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| Keywords: | Lymphoma,non-Hodgkin Lymphoma,diffuse Rearrangement,gene Research |
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