艾叶燃烧物清除自由基作用的观察

目的:研究艾叶燃烧物的药性作用.方法:以分光光度法测定艾叶燃烧物几种提取分离产物以及艾油清除1,1-二苯基-2-苦基肼(DPPH)自由基的能力,利用气相色谱-质谱(GC-MS)分析艾烟重组分化学成分与结构.结果:几种提取分离产物中艾烟重组分清除自由基能力最强;从中得到了36个可鉴定结构的化学成分,找出了一种抗氧化能力较强的物质5-叔丁基连苯三酚,其自由基清除率分别为维生素C和2,6-二叔丁基对甲酚(BHT)的1.55倍与1.21倍.结论:艾叶燃烧产物中的5-叔丁基连苯三酚清除自由基能力较天然抗氧化剂维生素C和人工合成抗氧化剂BHT均强.

Observation on scavenging free radical function of Artemisia burning products

Objective To study the pharmacologic action of Artemisia burning products. Methods The extractions of Artemisia burning products were determined by spectrophotometry. The scavenging ability of Artemisia burning products on DPPH was evaluated. The chemical components and structures of Artemisia burning products were analyzed by Gas Chromatography and Mass Spectrometry (GC-MS). Results The scavenging ability of extractions from Artemisia burning products was the strongest. Thirty-six chemical components were detected, and the 5-tert-Butylpyrogallol among them had a stronger anti-oxygen capacity, its scavenging free radical ability was 1.55 times and 1.21 times as strong as VitC and BHT, respectively. Conclusion The scavenging free radical ability of 5-tert-Butylpyrogallol extracted from Artemisia burning products is stronger than the natural antioxidant of VitC and artificial synthetic of BHT.