| 2种用药方案治疗心房颤动的成本-效果分析 |
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| 引用本文： | 邢建生.2种用药方案治疗心房颤动的成本-效果分析[J].中国药房,2008,19(14):1046-1047. |
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| 作者姓名： | 邢建生 |
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| 作者单位： | 宁夏医学院附属医院制剂科,银川市,750004 |
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| 摘 要： | 目的:比较胺碘酮与索他洛尔治疗心房颤动(AF)的成本与效果。方法:102例患者均分成A、B组,分别给予胺碘酮、索他洛尔治疗,并进行成本-效果分析。结果:2组成本分别为2714.18、2176.56元,有效率分别为78.43%、70.59%(P<0.01),不良反应发生率分别为13.73%、19.61%(P<0.01)。结论:胺碘酮转复房颤有效率与索他洛尔相当,但维持窦律疗效优于索他洛尔,对心脏毒副作用小于索他洛尔。
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| 关 键 词： | 心房颤动 胺碘酮 索他洛尔 成本-效果分析 |
| 文章编号： | 1001-0408(2008)14-1046-02 |
| 修稿时间： | 2007年9月6日 |
Amiodarone VS. Sotalol for Atrial Fibrillation: Cost-Effectiveness Analysis |
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| XING Jian-sheng.Amiodarone VS. Sotalol for Atrial Fibrillation: Cost-Effectiveness Analysis[J].China Pharmacy,2008,19(14):1046-1047. |
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| Authors: | XING Jian-sheng |
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| Institution: | XING Jian-sheng(Dept. of Pharmacy, The Affiliated Hospital of Ningxia Medical College, Yinchuan 750004, China) |
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| Abstract: | OBJECTIVE： To evaluate the cost - effectiveness of amiodarone versus sotalol for Atrial fibrillation. METHODS： A total of 102 patients with atrial fibrillation were treated with amiodarone （Group A） or sotalol （Group B） . The cost - effectiveness analysis was performed on two groups. RESULTS： The total cost in Group A was 2 714.18 yuan versus 2 176.56 yuan in Group B; the effective rates were 78.43% vs. 70.59% （P〈0.01）; and the incidences of adverse drug reactions （ADRs） was la. 7a% vs. 19.61% （P 〈 0.01）. CONCLUSION ： There is no significant difference between amiodarone and sotalol in effective rate of converting atrial fibrillation to sinus rhythm. However amiodarone is more effective than sotalol in maintenance of sinus rhythm. The ADR of amiodarone on heart is less severe than that of sotalol. |
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| Keywords: | Atrial fibrillation Amiodarone Sotalol Cost - effectiveness analysis |
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