速避凝治疗急性脑梗死临床疗效观察

目的 探讨速避凝治疗急性脑梗死的临床疗效和安全性。方法 73例发病48h内的急性脑梗死病人随机分成治疗组 (37例 )、对照组 (36例 ) ;治疗组用速避凝0.4ML脐周皮下注射 ,1次/12h、对照组用低分子右旋糖酐500ML静滴 ,1次/d ,两组治疗均为14d。治疗前后分别进行神经功能缺损评分及查血常规、肝肾功能、凝血功能及血粘度。结果 治疗组显效率59.46%、有效率86.49% ;对照组显效率36.11%、有效率63.89% ,两组比较有显著性差异 (P<0.05) ,且未发现有严重的肝肾功能损害及出血等副作用。结论 速避凝治疗急性脑梗死安全有效 ,疗效优于低分子右旋糖酐

Clinical observation of therapy effect of heparine on acute cerebral infarction

Objective To study the therapy effect and reliability of heparine on acute cerebral infarction. Method 73 patients with attact of acute cerebral infarction in 48 hours were randomzed into therapy group(n=37) and control group(n=36). Therapy group was treated with Subcutaneous injection of heparine at a dose of 0.4 ml/12h. Controlgroup was treated with infusion of low molecular dextran at a dose of 500ml/24h. All patients were treated for 2 weeks and the neurologic impairmen, liver function, renal function, blood coagulation function and whole blood test were detected and evaluated. Result 59.46% patients of therapy group showed the therapy effect , the utility rate is 86.49%, higher than that of control group(P<0.05). No side effects such as functional lesion of liver and renal were found in two group.Conclusion heparine is a safe and effective treatment for acute cerebral infarction. It has better effect than low molecular dextran.