| 布洛芬口服滴剂药效学实验研究 |
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| 引用本文： | 詹大志,朱正纲.布洛芬口服滴剂药效学实验研究[J].中南大学学报(医学版),2002,27(3):233-234. |
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| 作者姓名： | 詹大志 朱正纲 |
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| 作者单位： | 中南大学湘雅医学院保健科,长沙,410078 |
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| 摘 要： | 目的 :对布洛芬口服滴剂与布洛芬片剂进行药效学比较。方法 :采用布洛芬口服滴剂观察对角叉胶所致大鼠足跖炎性肿的抗炎作用、解热和镇痛作用 ;内毒素所致家兔体温升高的解热作用和醋酸所致小鼠疼痛的镇痛作用。结果 :布洛芬口服滴剂有明显的抗炎、解热和镇痛作用。结论 :布洛芬口服滴剂药效与片剂相同
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| 关 键 词： | 布洛芬 药物评价 动物 实验 |
| 文章编号： | 1000-5625(2002)03-0233-02 |
| 修稿时间： | 2001年8月20日 |
Experimental research on drug evaluation of ibuprofen oral drop |
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| ZHAN Da zhi,ZHU Zheng gang.Experimental research on drug evaluation of ibuprofen oral drop[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2002,27(3):233-234. |
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| Authors: | ZHAN Da zhi ZHU Zheng gang |
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| Institution: | (Health care Section,Xiangya School of Medicine,Central South University, Changsha 410078,China) |
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| Abstract: | Objective To make a pharmaceutical comparison between ibuprofen oral drop and ibuprofen tablet. Methods Using ibuprofen oral drop, we observed the anti inflammatory and analgesic effects of ibuprofen oral drop on the inflammatory swelling of the rats' toe caused by diagonal carrageenin; its anti thermic effect on the temperature rising of domestic rabbits caused by endotoxin; and its analgesic effect on mice's pain caused by acetic acid. Results Ibuprofen had obvious anti inflammatory and analgesic functions. Conclusion Ibuprofen oral drop has the same pesticide effect as that of ibuprofen tablet. |
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| Keywords: | ibuprofen drug evaluation animals laboratory |
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