| 应用IL-2加BCG与MMC配合手术治疗膀胱癌疗效分析 |
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| 引用本文： | 刘志斌,毛和平.应用IL-2加BCG与MMC配合手术治疗膀胱癌疗效分析[J].新乡医学院学报,1999,16(3):224-225. |
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| 作者姓名： | 刘志斌 毛和平 |
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| 作者单位： | 新乡医学院三附院外科!河南新乡，453003 |
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| 摘 要： | 目的探讨预防膀胱癌术后复发的更有效的方法。方法采用术前术后灌注白细胞介素2（IL-2）加卡介苗（BCG）或丝裂霉素C（MMC）以及术中膀胱粘膜下，切缘注射IL－2或MMC治疗60例膀胱癌患者，分别观察两组的疗效，并进行比较分析。结果随访5～52mo，IL－2＋BCG组复发率明显低于MMC组（P＜0．05）。结论采用IL－2＋BCG组的方法预防膀胱癌术后复发安全有效。
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| 关 键 词： | 膀胱肿瘤 白细胞介素2 卡介苗 丝裂霉素C |
Bladder cancer treated by IL-2 add BCG or MMC cooperate operation |
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| LIU Zhi-Bin, MAO He-Ping.Bladder cancer treated by IL-2 add BCG or MMC cooperate operation[J].Journal of Xinxiang Medical College,1999,16(3):224-225. |
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| Authors: | LIU Zhi-Bin MAO He-Ping |
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| Abstract: | Objective To researh the effective method to reduce the recurrence rate of bladder cancer. Methods 60 patients with bladder cancer were treated by injecting interleukin - 2(IL - 2) or MMC(mitomycin) into the under mucosa and the bladder incision edges during the operation and instilling IL - 2 add Bacillas Calmette- Guerin (BCG) or MMC intravesically before and after the operation. Results All patients were followed up for 5~52 months. The recurrence rate with IL - 2 add BCG was lower than the recurrence rate with MMC(P<0.05). Conclusions It is suggested that this method with IL-2 add BCG therapy to prevent bladder tumor recurrence is safe and effective. |
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| Keywords: | bladder cancer interleukin-2 bacillas Calmette-Guerin cmitomycin |
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