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Primary thyroid marginal zone B-cell lymphoma MALT-type in a patient with rheumatoid arthritis
Authors:Songul Serefhanoglu  Umit Tapan  Ihsan Ertenli  Umut Kalyoncu  Aysegul Uner
Affiliation:(1) Division of Hematology, Department of Internal Medicine, Hacettepe University Hospital, Sıhhiye, 06100 Ankara, Turkey;(2) Division of Rheumatology, Department of Internal Medicine, Hacettepe University Hospital, Sıhhiye, Ankara, Turkey;(3) Department of Pathology, Hacettepe University Hospital, Sıhhiye, Ankara, Turkey
Abstract:Autoimmune diseases are defined as specific, adapted immune reactions against self antigens. Immune mechanism deficiency is a causal factor for B-cell lymphoma in primary Sjögren’s syndrome and autoimmune thyroid disease. Thyroid mucosa-associated lymphoid tissue (MALT) lymphoma is a 67-fold and parotid lymphoma is a 44-fold increased risk in Sjögren’s syndrome and thyroiditis. MALT lymphoma was not reported in rheumatoid arthritis. We herein report the case of a 56-year-old woman with maltoma of thyroid in rheumatoid arthritis patient.
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