| 肝舒康冲剂防治二甲基亚硝胺致大鼠肝纤维化的实验研究 |
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| 引用本文： | 姜德友,王远红,吴艳敏,张琪. 肝舒康冲剂防治二甲基亚硝胺致大鼠肝纤维化的实验研究[J]. 中西医结合肝病杂志, 2000, 10(4): 21-22 |
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| 作者姓名： | 姜德友 王远红 吴艳敏 张琪 |
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| 作者单位： | 1. 黑龙江中医药大学,哈尔滨,150040
2. 哈尔滨-洲制药有限公司 |
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| 基金项目： | 黑龙江省中医管理局资助课题(96019) |
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| 摘 要： | 目的：研究肝舒康冲剂对肝纤维化的防治作用。方法：采用二甲基亚硝胺）ＤＭＮ）所致大鼠肝纤维化模型，研究肝舒康冲剂对大鼠血清透明质酸（ＨＡ）和Ⅲ型胶原（ＰＣⅢ）及病理组织形态学的影响。结果：肝舒康冲剂能降低肝纤维化血清学指标ＨＡ、ＰＣⅢ数值，改善肝组织病理损害，明显优于对照组（Ｐ〈０．０５－０．０１）。结论：肝舒康冲剂具有良好的预防和治疗肝纤维化效果。
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| 关 键 词： | 肝舒康冲剂 二甲基亚硝胺 肝纤维化 治疗 |
| 修稿时间： | 2000-01-21 |
Experimental Study on the Effect of Ganshukang Granule on Treating Fiberized Liver in Rats Leaded by Dimethylnitrosamine |
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| Jiang Deyou,Wang Yuanhong,WuYanmin,et al.. Experimental Study on the Effect of Ganshukang Granule on Treating Fiberized Liver in Rats Leaded by Dimethylnitrosamine[J]. Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases, 2000, 10(4): 21-22 |
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| Authors: | Jiang Deyou Wang Yuanhong WuYanmin et al. |
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| Affiliation: | Herbin 150040 |
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| Abstract: | Aim: To study the effect of Ganshukang granule (GSK) on preventing and treating experimental fiberized liver in rats. Method: The animal model of fiberzed liver in rats was set up with DMN. The effect of GSK (medicine to be taken affter being mixed with boiling water, wine, etc) on HA. PC I and pathology of fiberized liver were observed. Result: The result showed that GSK is effective for treating fiberized liver in rats. The HA. PC I and liver cells were improved much better than that in control group (P<0. 05-0. 01). Couclusion: GSK have antifiberized function obviously. |
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| Keywords: | Ganshukang Granule Dimethylnitrosamine (DMN) Fiberzed Liver Rats |
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