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Biochemical adaptations in cardiac muscle: effects of physical training on sulfhydryl groups of myosin. |
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| Authors: | A Bhan A Malhotra J Scheuer |
| Affiliation: | 1. Department of Medicine, Montefiore Hospital and Medical Center, Bronx, New York, U.S.A.;2. the Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, U.S.A.;3. the Department of Physiology, Albert Einstein College of Medicine, Bronx, New York, U.S.A. |
| Abstract: | Myosin ATPase activity is increased in the hearts of rats exercised by swimming. There is no difference in the total amount of sulfhydryl groups in the myosin from the control and exercised groups. The difference seems to reside in the reactivity of the sulfhydryl groups at or near the active site as evidenced by (a) decreased stimulation of the ATPase activity by iodoacetamide and (b) decreased incorporation of 14C-IAA in the myosin from the hearts of the exercised animals as compared to the controls. |
| Keywords: | Cardiac muscle Myosin ATPase Sulfhydryl groups Physical training |
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