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eIF2β, a subunit of translation‐initiation factor EIF2, is a potential therapeutic target for non‐small cell lung cancer
Authors:Ichidai Tanaka  Mitsuo Sato  Toshio Kato  Daiki Goto  Tomohiko Kakumu  Ayako Miyazawa  Naoyuki Yogo  Tetsunari Hase  Masahiro Morise  Yoshitaka Sekido  Luc Girard  John D. Minna  Lauren A. Byers  John V. Heymach  Kevin R. Coombes  Masashi Kondo  Yoshinori Hasegawa
Affiliation:1. Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan;2. Department of Cancer Genetics, Nagoya University Graduate School of Medicine, Nagoya, Japan;3. Division of Cancer Biology, Aichi Cancer Center Research Institute, Nagoya, Japan;4. Hamon Center for Therapeutic Oncology Research, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA;5. Department of Thoracic/Head & Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;6. The University of Texas Graduate School of Biomedical Sciences, Houston, TX, USA;7. Department of Biomedical Informatics, Ohio State University, Columbus, OH, USA;8. Department of Respiratory Medicine, Fujita Health University, Toyoake, Japan
Abstract:
Keywords:adenocarcinoma  eukaryotic initiation factor‐2  G1 phase cell cycle checkpoints  heterotrimeric GTP‐binding proteins  RNA interference
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