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PD‐L1 expression is mainly regulated by interferon gamma associated with JAK‐STAT pathway in gastric cancer
Authors:Kousaku Mimura  Jun Liang Teh  Hirokazu Okayama  Kensuke Shiraishi  Ley‐Fang Kua  Vivien Koh  Duane T. Smoot  Hassan Ashktorab  Takahiro Oike  Yoshiyuki Suzuki  Zul Fazreen  Bernadette R. Asuncion  Asim Shabbir  Wei‐Peng Yong  Jimmy So  Richie Soong  Koji Kono
Affiliation:1. Department of Gastrointestinal Tract Surgery, Fukushima Medical University, Fukushima, Japan;2. Department of Advanced Cancer Immunotherapy, Fukushima Medical University, Fukushima, Japan;3. Department of Progressive DOHaD Research, Fukushima Medical University, Fukushima, Japan;4. Department of Surgery, National University Health System, Singapore, Singapore;5. First Department of Surgery, University of Yamanashi, Yamanashi, Japan;6. National University Cancer Institute Singapore, National University Health System, Singapore, Singapore;7. Department of Internal Medicine, Meharry Medical College, Nashville, TN, USA;8. Department of Medicine and Cancer Center, Howard University, Washington, DC, USA;9. Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan;10. Department of Radiation Oncology, Fukushima Medical University, Fukushima, Japan;11. Cancer Science Institute of Singapore, Singapore, Singapore;12. Department of Pathology, National University of Singapore, Singapore, Singapore
Abstract:
Keywords:CD8  gastric cancer  IFN‐γ    PD‐L1  TILs
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