肺外周肿瘤超声造影与增强CT诊断的对比研究

目的 探讨肺外周肿瘤对比增强超声造影(CEUS)与增强CT(CECT)的价值对比.方法 对35例患者均经病理证实的肺外周肿瘤进行了CEUS和CECT检查的对照.CEUS采用造影剂六氟化诺(剂声诺维)和低机械指数实时超声成像技术.CECT采用造影剂碘普罗胺(商品名优维显),行平扫加增强扫描.结果 35例患者超声造影增强后肺外周肿瘤表现为高增强20例(57.1%),低增强14例(40%),无增强1例(2.9%);CECT表现为高增强15例(42.9%),低增强19例(54.3%),无增强1例(2.9%);肿瘤CEUS表现为不均匀增强24例(68.6%),均匀增强10例(28.6%),1例无增强(2.9%);CECT表现为不均匀增强26例(74.3%),均匀增强8例(22.9%),1例无增强(2.9%);分析CEUS与CECT增强水平和增强程度存在的差异无统计学意义,肿瘤的CT增强值(HU)和B超增强值(dB)相关性较高.结论 超声造影对肺外周肿瘤的诊断价值可与增强CT相当.

Enhancement pattern of peripheral lung carcinoma: comparison between contrast-enhanced uitrasonography and contrast-enhanced computed tomography

Objective To compare the enhancement pattern of low mechanicalindex contrast-enhanced ultrasonography (CEUS) in peripheral lung carcinoma with contrast-enhanced helical CT (CECT).Methods Thirty-five patients with peripheral lung carcinoma underwent CEUS performed with the contrastagent SonoVue at a low mechanical index contrast specific mode and CECT performed with the contrast agentUltravist at a standard biphasic helical CT scaning protocol. The enhancement pattern related to tumorvascularity was analyzed. Results By using contrast-enhanced sonography, hyper-enhancement patterns weremanifested in 57.1% (20/35) of the lesions and hypo-enhancement in 40% (14/35); both notsignificantly different from those manifested by using CECT 42.9% (15/35) and 54. 3% (19/35) of thelesions respectively, both P > 0.05 ]. By using CEUS, inhomogenous enhancement pattern rate in the lesionswas 68.6% (24/35) and the homogeneous enhancement rate was 28.6% (10/35), both not significantlydifferent from those of the CECT group 74.3% (26/35) and 22.9% (8/35) respectively, both P> 0.05 ].The non-enhancement rates of CEUS and CECT groupd were both 2.9% (1/35). The enhancement intensitydB value of the CEUS group was positively correlated with the CT value of the CECT tumors ( r = 0.836,P <0.001 ). Conclusion The diagnotic value of contrast-enhanced sonography is similar to that ofenhancement CT in detecting peripheral lung carcinoma's vascularity.