Community acquired pneumonia (CAP) caused by Cryptococcus neoformans in a healthy individual |
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| Authors: | Nakamura Shigeki Miyazaki Yoshitsugu Higashiyama Yasuhito Yanagihara Katsunori Ohno Hideaki Hirakata Yoichi Shikuwa Masahiro Mizuta Yohei Tashiro Takayoshi Kohno Shigeru |
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| Affiliation: | Second Department of Internal Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan. |
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| Abstract: | A 41-y-old male had been diagnosed as having community acquired pneumonia (CAP) with consolidations in the chest radiograph, fever and cough. Since clarithromycin and ss-lactam agents were not effective, bronchoscopic examination was performed. Indian ink staining of bronchial wash smears revealed yeast-like cells with a thick capsule, and Cryptococcus neoformans was isolated several d later. Serum glucuronoxylomannan antigen was > or = x 1024. The patient was treated with itraconazole for 16 weeks. |
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